Methods of validating research

Posted by / 06-Feb-2020 05:14

These specifications should be intended to assure a nonsignificant risk of false results. Reverend Thomas Bayes (1702-1761) developed a probabilistic model for defining the likelihood that an element would be a member of a specific class.

In contrast to the verification explanation, validation is directly related to the interested parties requirements, such as the accuracy of clinical decision required by the patients.Verification and validation definitions are sometimes confusing in practice.ISO defines verification as the “confirmation, through the provision of objective evidence, which specified requirements had been fulfilled” (3.8.12 of [2]).So, the model determines the probability of a patient or a healthy individual to be truly classified as infected or noninfected.This classification is referred as diagnostic sensitivity Se[%] when “the percentage (number fraction multiplied by 100) of subjects with the target condition (as determined by the diagnostic accuracy criteria) whose test values are positive”, and diagnostic specificity Sp[%] when “the percentage (number fraction multiplied by 100) of subjects without the target condition (as determined by the diagnostic accuracy criteria) whose test values are negative” (5.3 of [3]).

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